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BPC-157: More localized, especially in the GI tract and connective tissue TB-500: Broader systemic effects, influencing cell migration and circulation In some cases, both may be considered together (bpc157 and tb500) as complementary, though decisions must be individualized and physician-guided
5 Comparison: Wegovy effects by IBS subtype Notably, a 2025 systematic review found that GLP-1 receptor agonists significantly reduced pain intensity in patients with IBS
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