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Implications for the GLP-1 market: More employers will get ahead of the high costs associated with rising GLP-1 use by significantly restricting or eliminating coverage for the drugs, particularly as new oral formulations broaden their appeal

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PHGDH, the first SSP enzyme, is markedly upregulated in HCT-116 colon cancer cells, in contrast to normal colonic epithelial cells, which exhibit only basal levels of expression