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Importantly, tirzepatide is not metabolized through the cytochrome P450 enzyme system, and renal impairment has minimal impact on its exposure
It is injected under the skin in the: Abdomen Thigh Upper arm To ensure safe and comfortable use: Rotate injection sites weekly to reduce irritation Avoid injecting into the same area repeatedly Follow the technique provided by your clinician Key Safety Rules to Follow Only use the prescribed dose : Do not increase or combine injections without medical advice Missed dose : Take it within a few days if remembered, otherwise skip and continue your schedule Storage : Keep pens refrigerated and avoid exposure to extreme temperatures Monitor your response : If weight loss plateaus or side effects become difficult, seek clinical advice Gradual dose progression helps your body adjust and reduces the likelihood of side effects
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