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Consequently, simulations suggest that while doxorubicin redox metabolism impacts GSH metabolism, the concentrations required to illicit a toxic response, with either a single or extended exposure, reside outside that of the therapeutic dosing range

People with mild sleep apnea generally have about five to 14 interruptions per hour, he said, while those with moderate sleep apnea have 15 to 30 interruptions, and patients with severe sleep apnea have more than 30 an hour

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