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Neuroprotective effects of GLP-1 were also seen in other cells in the retinal microenvironment, including RPE and glial, including astrocytes and Mller cells
Although the overall structures of retatrutide-bound GLP-1R, GIPR and GCGR are highly similar, with C root mean square deviation (RMSD) values of 0.880.93 , unique structural features were noted at ECL1, ECL3 and the extracellular tips of TM1, TM3 and TM7, displaying receptor-specific positions and conformations
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10.1093/eurheartj/ehz953 47
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