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[Abstract] Compared with guinea pigs receiving periocular injections of vehicle (5 mM, 10 L on days 1, 4, 7, 10, and 13 over two weeks), those treated with glutathione oxidized (Glu, 20 mg/mL, 10 L on the same schedule) exhibited a 1.76-fold increase in relative myopia, along with a 1.78-fold increase in axial length (AL)
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Arg, Ala, Glu and Tyr were selected as replacements to distinguish the relevance of the charge and size of the side chain and to mimic tyrosine-dependent glutathione transferases 3,18
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