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Aminullah N, Mostamand A, Zahir A, Mahaq O, Azizi MN

Efficacy-to-tolerability ratio is lower for female rats on GLP1R agonists As a first step to investigate biological mechanisms underlying sex differences in the response to GLP1R agonists, we administered a single dose of semaglutide or tirzepatide in male and female Wistar rats across a wide range of doses (0.0003 mg/kg up to 0.3 mg/kg

In short, Wegovy and Ozempic are essentially identical medications under different brand names, with the primary difference lying in the dosage of semaglutide in each injection pen and the specific approvals granted for their use