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Additionally, GCN2 expression in macrophages and MDSCs promotes their suppressive function, restraining antitumor immunity in mouse models of colon cancer and melanoma [153]

In clinical trials, constipation rates with cagrilintide ranged from approximately 10% to 25% depending on the dose, compared to roughly 5% to 8% with placebo

Carotenoids, such as -carotene, lutein, astaxanthin, and lycopene, not only have antioxidant effects but can also be converted into Vitamin A, participating in a variety of physiological processes [418]