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1.2% placebo in SUSTAIN-1 Typical onset / first 4 to 8 weeks of titration, dose-dependent Median duration / most episodes resolve within 10 to 14 days at each dose step Top dietary strategy / small meals (200 to 300 kcal) every 3 to 4 hours Key soluble fiber sources / oats, peeled potatoes, white rice, ripe bananas Foods to limit / high-fat meals, sugar alcohols, raw cruciferous vegetables Hydration target / 1 to 1.5 L oral rehydration solution per day during active symptoms When to escalate / more than 6 loose stools daily, blood in stool, or signs of dehydration Dose adjustment / Novo Nordisk prescribing information allows 4-week dose-step delays Probiotic evidence / Lactobacillus rhamnosus GG shows modest benefit for drug-induced diarrhea Why Ozempic Causes Diarrhea Semaglutide is a GLP-1 receptor agonist that slows gastric emptying by 10% to 30%, but its effects on the lower gut are more nuanced

Number of Sessions More sessions mean higher overall cost

However, growth hormone continues to play an important role throughout adult life

Clinical studies have produced similar results, with GLP-1RAs reducing cognitive impairment in patients with T2DM