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However, in UC, microbial invasion or epithelial barrier disruption leads to the recruitment of inflammatory macrophages expressing intermediate CX3CR1 levels (CX3CR1 int ), derived from circulating CX3CR1 low Ly6C high CCR2 + monocytes

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10.1172/jci.insight.93382 Summary Keywords glucagon-like peptide-1 receptor agonists, ocular diseases, glaucoma, diabetic retinopathy, mechanism Citation Xie Z, Yang Z, Tian D and Chen Y (2025) Unlocking the potential of GLP-1 receptor agonists in ocular therapeutics: from molecular pathways to clinical impact