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To overcome these limitations, this review discusses a range of structural modifications, including N-terminal and C-terminal substitutions, fatty acid conjugation, and large molecule fusion technologies, which have collectively contributed to enhanced half-life, increased stability, improved receptor affinity, and retained or augmented bioactivity of GLP-1 analogs
PMID: 31910118
4.5 Neurodegenerative diseases 4.5.1 Microglial polarization in AD/PD In Alzheimers disease (AD) and Parkinsons disease (PD), disrupted microglial polarization is a central mechanism driving neuroinflammation and neurodegeneration
Thats why we use natural sweeteners like stevia, allulose, and monk fruit instead as well as natural coloring and flavoring derived from fruits and other foods
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