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The GOT1-mediated glutamine metabolic pathway is a critical survival mechanism when the major glutamine pathway is inhibited, and it promotes tumorigenesis and development by replenishing the tricarboxylic acid (TCA) cycle, maintaining redox homeostasis, and providing the essential precursor, aspartic acid (Asp), for nucleotide production
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iScience 26 (9), 107722
& Welch, H
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