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Sulfur-containing residues are the most susceptible ones to ROS attack

Copper in its metallic state has no effect on the skin and it becomes a potential irritant or allergen when it is corroded to become soluble through the action of exudates encountered on the skin surface, or in a relatively corrosive physiological environment such as the oral cavity or the uterus 3

Certain micronutrients, especially minerals such as magnesium and zinc, act as cofactors for enzymes involved in cellular processes, including protein synthesis