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The first step is to react commercially available IR-780 iodide with excess anhydrous piperazine in anhydrous N , N -dimethyl formamide at 85 C to form cyanine-piperazine (CP)
Its the only other FDA-approved oral peptide drug that relies on a permeation enhancer
Zepbound contains tirzepatide and should not be used with other tirzepatide-containing products or any GLP-1 receptor agonist medicines
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