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It is used solely as a research tool for exploring peptide-driven signalling mechanisms in vitro, and no conclusions about biological effects in humans or animals should be drawn from this work
Moreover, the incidence of serious side effects or infusion reactions was low
To address this, we co-transfected MBP-tagged c-Jun with the DDD-Ube2e2-COP1 complex and performed tandem purification steps (Fig
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