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So, peripherally dosed long-acting GLP-1RAs have the ability to access neurons in both the CVOs and in a few select sites in the hypothalamus, but do not broadly cross the blood brainbarrier
On the other hand, Semaglutide mimics the activity of GLP-1, a hormone naturally released by the intestines in response to intake of food
It is free from gluten, soy, dairy, and artificial additives, making it suitable for a wide range of dietary needs
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