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A Mendelian randomization study found a causal relationship between TMAO and its precursors and susceptibility to hypertension
Both were removed from the FDA's Category 2 interim compounding bulks list in September 2024 following nominators' withdrawal, and the FDA's Pharmacy Compounding Advisory Committee subsequently recommended against including them on the 503A Bulks list, leaving compounding in regulatory limbo as of early 2026
Guerrero, K
Sonnenburg JL, Bckhed F (2016) Diet-microbiota interactions as moderators of human metabolism
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