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To identify the key mediator of folate-induced T cell exhaustion, we used small interfering RNA (siRNA) to knock down FOLR2 and SLC19A1 expression in T cells prior to folate exposure
AVE3085 is a novel synthetic agent that acts as an eNOS transcription enhancer
The standardization of platforms, reproducibility of results, and harmonization with traditional pathology are ongoing challenges
Research data supporting these mechanisms is widely available in global biomedical databases
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