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Sharma et al., 2023)
Small molecule GLP-1 agonists in the clinic Orally dosed small molecule receptor agonists of GLP-1R such as danuglipron, lotiglipron and orforglipron (Figure 1) have been discovered and have progressed into clinical trials
No obstante, y de acuerdo a las conclusiones de investigaciones llevadas a cabo por expertos , la administracin exgena de esta molcula ha arrojado resultados positivos en diferentes aplicaciones como las que te enumeramos: Cardiovasculares
Some are approved for diabetes, some for chronic weight management, and some may be discussed off-label based on the providers clinical judgment
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