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Recent metanalysis have revealed significant increase in oxidative stress markers such as MDA and a substantial depletion of antioxidants such as catalase, GSH in the blood, and postmortem brain of PD patients compared to healthy controls 25
Removal of bioactive GLP-1 is a consequence of N-terminal proteolysis catalyzed by dipeptidyl peptidase IV (DPP IV or DPP4)
Your maintenance dose might be lower than your peak dose, but completely discontinuing medication removes the metabolic support keeping your appetite normalized and your weight stable
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