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Conversely, blocking the Notch signal leads to the expression of Atoh1 , which induces secretory progenitors [20]
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Chemogenetic inhibition of DMH LepR neurons led to increased food intake by increasing the number of licking bouts without altering bout length, in contrast to the increased bout duration in DMH GLP-1R neurons, implying that DMH LepR neurons play a role in satiety [48]
However, he added, that there is still issues with the limited supply for branded weight-loss drugs
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