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The drugs mimic a naturally produced hormone called GLP-1 which regulates hunger, slows digestion, and regulates insulin release
Other companies, including Terns Pharmaceuticals (TERN-601), Structure Therapeutics (GSBR-1290), and Viking Therapeutics, have oral GLP-1 programs at earlier stages of development, but none has reached Phase 3 or generated the depth of clinical data available for orforglipron
Understanding the underlying cause is essential, and discussing any weight changes with your GP ensures proper diabetes management whilst addressing your concerns about treatment outcomes
Known as glucagon-like peptide 1 or GLP-1 receptor agonists, these drugs were originally developed to treat type 2 diabetes
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