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+ It is used as an inhibitor of nicotinamide N-methyltransferase, the enzyme that transfers a methyl group from SAM to nicotinamide to form 1-methylnicotinamide and SAH
More specifically it has been posited to regulate the cellular actin-cytoskeleton and cellular migration by sequestering G-actin
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hence, addition of intrinsic factor in the second step results in an increase in vitamin B 12 absorption (over the baseline established in the first)
