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Long-acting agents (weekly formulations, liraglutide daily) provide sustained GLP-1 activity day-long, improving fasting and postprandial glucose with less fluctuation
Gut microbiota and intestinal FXR mediate the clinical benefits of metformin
FIGURE 1 Rather than attempting confirmatory quantitative synthesis across all outcomes, we deliberately restricted quantitative analysis to a methodological demonstration
It is a mechanical explanation that complements the pharmacological one
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