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This might explain why some patients feel worse even with smaller doses of ibuprofen
In PDB ID 1nu8, Diprotin A forms a tetrahedral intermediate, where the C atom of the carbonyl group of Pro2 in Diprotin A was found in a tetrahedral configuration (grey ball in Figure 5) covalently linked to Ser630
doi: 10.1016/j.antiviral.2017.03.014 415 BabaeiFNassiri-AslMHosseinzadehH
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