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This is especially important if you tend to be sensitive to caffeine, as small changes in timing or quantity can significantly reduce the likelihood of experiencing headaches

(2025) Implications of the European Association for the Study of Obesitys New Framework Definition of Obesity: Prevalence and Association With All-Cause Mortality Yang, Shijie, et al

Particular attention is needed for insulin and sulfonylureas (hypoglycemia risk), oral contraceptives (reduced absorption), thyroid medications (altered absorption timing), and blood thinners (variable absorption)

Fiber also supports digestion, which can be helpful when medications slow gastric emptying