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Reported side effects included: Nausea (most common, particularly during dose escalation) Vomiting Diarrhea Constipation Decreased appetite (this is also the mechanism, so it is both a side effect and the goal) Discontinuation due to side effects in the Phase 2 trial was around 16% in the highest dose group
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Quitting smoking improves multiple cardiovascular and metabolic risk factors
These data suggest the potential of semaglutide and similar drugs to fill an unmet need for the treatment of alcohol use disorder, said senior author Klara Klein of the University of North Carolina School of Medicine
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