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Exciting experimental evidence available in patients with NASH suggests the potential of LG to reduce lipotoxicity by improving adipose tissues insulin sensitivities (129)
Crucially, unlike full-length hGH, AOD-9604 does not significantly elevate IGF-1 levels or negatively impact glucose tolerance, contributing to its favorable safety profile in clinical studies
Altogether, this leads to weight lossan average of 15% body weight, per a study published in the The New England Journal of Medicine
Research in animal models shows activity at approximately 0.5mcg/kg, though human protocols typically use standardized doses in the 1-3mg range regardless of body weight
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