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Research protocols frequently specify administration on an empty stomach because elevated blood glucose and insulin can blunt the GH-release response in research models
If you have hypothyroidism or hyperthyroidism, ensure these conditions are well-controlled before starting GLP-1 therapy
Before beginning, gather all necessary supplies, including your injection pen, a new disposable needle, alcohol swabs, and a sharps container
GLP-1/GIP medications can cause muscle loss alongside fat loss if protein intake is inadequate
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![Mechanism of action of GLP-1 [25]](https://www.researchgate.net/profile/Asfandyar-Sheikh/publication/256289222/figure/fig1/AS:614177232142337@1523442671231/Mechanism-of-action-of-GLP-1-25.png)
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