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Although effective, these medications often present such side effects as skin rashes, fever, arthralgia, liver toxicity, and agranulocytosisan extreme decline in white blood cell count-that preclude their long-term use in certain patients (Mishra et al

boosting immunity and protecting the skin from everyday irritations like rashes and sunburn

CL Answer I thought the B vitamins were all water soluble and did not build up in the body, so you would not build up toxic levels

Traditionally it has been diagnosed with X-ray radiographs from different angles to look for joint space width (JSW) and asymmetry, and for the presence of osteophytes