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Los agonistas del receptor GLP-1 actan de varias maneras simultneas : estimulan la secrecin de insulina cuando los niveles de glucosa estn elevados, suprimen la liberacin de glucagn (hormona que aumenta el azcar en sangre), retrasan el vaciamiento gstrico y reducen el apetito actuando sobre centros del cerebro que regulan la saciedad
10.1016/j.cbi.2019.05.040 22 ChenY
In -cell specific null mutants, the increase in -cell mass with exendin-4 treatment is lost along with the increases in -cell proliferation and insulin content
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