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These findings have positioned 5-Amino-1MQ as a useful molecular tool for probing upstream metabolic regulation
Concurrent medications (metformin, PPIs, antibiotics) and underlying gastrointestinal conditions may cause diarrhoea coinciding with B12 supplementation
B12 injections are clinically indicated for patients with confirmed deficiency or malabsorption conditions, including those with pernicious anaemia, gastrectomy, ileal resection, Crohn's disease, or neurological symptoms related to B12 deficiency
Newer surgeries, however, have been developed that can preserve fecal continence by using part of the ileum to create a pouch that is connected to the intact rectal sphincter (Hwang 2008)
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