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Approvable documentation includes: "Patient has BMI 34.2 (measured 3/15/2026, height 5'6", weight 211 lbs) and hypertension (documented BP 148/94 on two visits)
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The cAMP elevation from GHRH-R primes the somatotroph by activating protein kinase A, which phosphorylates voltage-gated calcium channels to increase their open probability, meaning the subsequent calcium surge from GHS-R1a activation encounters a cell already poised for maximal exocytosis
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