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For example, saxagliptin protected the mitochondrial function in PD rat models by up-regulating complex I and the anti-apoptotic protein Bcl-2 (72), while long-term use of exendin-4 in rodents promoted the function of hippocampal nerves, and improved motor function and behavior (73)
Injectable semaglutide (Wegovy injection) achieved approximately 15% weight loss in Phase 3 studies
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