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Dietary TMAO decreased glucose tolerance, increased insulin levels and insulin resistance (HOMA-IR), and increased inflammation in mice on a high-fat diet [20]

found that Gal prevented iron overload and lipid peroxidation in a MIRI model and significantly attenuated myocardial fiber damage, reduced cerebral infarct size, and improved cardiac function by targeting the GPX4/Nrf2 signalling pathway in mice after MIRI (Salama and Elshafey, 2021)

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