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In relation to the risk of developing cancer, a study published in The Journal of Clinical Endocrinology & Metabolism found no significant association between the dose of rhGH, mortality, and cancer incidence, making causality far less likely: Safety concerns have been raised regarding premature mortality, diabetes, neoplasia, and cerebrovascular disease in association with GH therapy
doi: 10.1021/acs.nanolett.2c01332 117 YangYCuiYCaoWZhaoMLinWXuRet al
Hidden Inflammatory Mechanism : These molecules activate the same inflammatory pathways as classical leukotrienes and may help explain persistent inflammation and variable responses to existing treatments
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