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The magnitude of weight change observed in some DIO studies appeared to exceed that reported for GLP-1R single agonists under comparable conditions in the same model systems [VERIFY]

Participants in the GLP-1RA group reported lower craving of alcohol overall, although craving did rise over the course of the drinking session, as in the control group

The identity of a receptor to which nicotinic acid binds allows for the development of new drug therapies that activate the same receptor but that may lack the negative side-effect of flushing associated with nicotinic acid

Counselling, lifestyle changes, and stress reduction remain important