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Common side effects of Mounjaro include: Gastrointestinal disturbances nausea, vomiting, diarrhoea, constipation, and abdominal discomfort are the most frequently reported adverse effects, typically occurring during dose escalation and often improving with continued use Reduced appetite whilst therapeutically desired, some patients experience excessive appetite suppression Injection site reactions mild redness, itching, or discomfort at the injection site Fatigue and dizziness particularly during the initial treatment period Hypoglycaemia mainly a risk when used with insulin or sulfonylureas, which may require dose adjustment of these medications [1] [10] More serious but less common risks include: Gallbladder disease (cholelithiasis, cholecystitis) Dehydration potentially leading to acute kidney injury Pancreatitis Severe hypersensitivity reactions Potential worsening of diabetic retinopathy in people with diabetes, particularly with rapid improvement in blood glucose control [1] [11] In contrast, corticosteroid medications (such as prednisolone or dexamethasone) produce markedly different side effects, particularly with prolonged use

Common side effects of semaglutide use include stomach pain, heartburn, burping, nausea, vomiting, diarrhea, and constipation

Some people prefer taking it in the morning to align with their daily exercise routine, while others find it more convenient to take it in the evening

The timeline varies slightly based on injection strength and your individual metabolism