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Heart failure with preserved ejection fraction is characterized by dynamic impairment of active relaxation and contraction of the left ventricle on exercise and associated with myocardial energy deficiency
Conclusion: Both 36-week SSR and 48-week SSR demonstrate similar efficacy in biochemical response and histological improvements with good safety, which support 36-week SSR as a preferable therapeutic choice
Front Pharmacol 10:484
The second is blanket dismissal the position that anything without a large randomized controlled trial has no clinical value
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