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One way that insulin resistance affects hormones is by disrupting the function of the hypothalamic-pituitary-adrenal (HPA) axis, which is a complex system that regulates the bodys stress response.In insulin resistance, the body produces more cortisol, a stress hormone that can lead to a range of negative effects, including weight gain, increased appetite, and decreased insulin sensitivity
11,12 Moreover, RWS provide opportunities to explore comparisons not tested in RCTs
Potential role of glucagon-like peptide-1 (GLP-1) receptor agonists in substance use disorder: a systematic review of randomized trials
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