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Administration of GLP-1 and exendin-4 promoted neurite outgrowth in cultured dorsal root ganglion (DRG) neurons, presumably explaining the increased nerve fibers observed in biopsies of IBS individuals [51]
Research shows sulforaphane reduces inflammatory markers (IL-1, IL-6, iNOS) in aged microglia while upregulating Nrf2 target genes
This might especially be the case in tumours, which downregulate aldolases such as hepatocellular carcinomas where lower aldolase B levels are linked to a poor prognosis 71
Prescriptions for GLP-1s have more than quadrupled since 2020, A 2024 KFF Health Poll survey found that as many as one in eight (12%) adults have taken a GLP-1 drug, with as many as 6% are currently using GLP-1 drugs
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