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The condition is often described in four broad stages: Numbness, tingling, or pain occurs occasionally, often at night or during specific hand activities
Doubling increases your risk of severe nausea, vomiting, and dangerous blood sugar drops (especially if you're on insulin or sulfonylureas)
The upper arm averages 4 to 12 mm
Some patients carry genetic variants that enhance tirzepatide response, while others may need higher doses or alternative approaches
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