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Most cases can be managed conservatively without discontinuing the medication
The STEP 5 clinical trial showed that Wegovy causes sustained weight loss of 15.2% from baseline at 104 weeks (2 years) with weekly injection of semaglutide 2.4 mg
Grundy SM, Brewer Jr HB, Cleeman JI, Smith Jr SC, Lenfant C
For many patients, this can mean: GLP-1 therapy supports the metabolic side of weight management , helping the body respond more appropriately to food intake rather than relying on constant effort or restriction alone
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