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This hypothesis proposes that small vessel disease in brain regions controlling mood contributes to depression, particularly in older adults
This indicates protein aggregation or bacterial contamination
on the other hand, enhancing -arrestin-2 action by the overexpression of G protein receptor kinase 5 (GRK5) increases GLP-1R endocytosis 35
Both contain semaglutide, but Wegovy is licensed for weight management at doses up to 2.4 mg a week (and 7.2 mg a week from 2026), while Ozempic is licensed for type 2 diabetes at doses up to 2 mg a week
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