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Deletion of the homocysteine thiolactone detoxifying enzyme bleomycin hydrolase in mice causes memory and neurological deficits and worsens Alzheimers disease-related behavioral and biochemical traits in the 5xFAD model of Alzheimers disease
Metabolic pathway impact was calculated by Global ANOVA pathway enrichment and Out-degree Centrality Topology analysis through the MetaboAnalyst 4.0 software 91 , using KEGG library (2019) as a reference
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At first, injections are given daily or every other day to quickly increase vitamin B12 levels
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