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Primary carnitine deficiency PCD is a rare genetic disease caused by mutations in the SLC22A5 gene, which leads to dysfunction of the carnitine transporter OCTN2, thereby hindering the entry of carnitine from the blood into cells and the reabsorption of carnitine by the kidneys

We tested the hypothesis that retatrutide like the -adrenoceptor agonist isoprenaline raises force of contraction (FOC) in isolated electrically driven (1 Hz) left atrial preparations (LA) and exerts positive chronotropic effects (PCE) in isolated spontaneously beating right atrial preparations (RA) from adult CD1 mice

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