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While this is a necessary first step, it frequently creates highly reactive, electrophilic intermediate metabolites that are actually more toxic and dangerous than the original parent compound
[7] [8] However, much of the mechanistic evidence underpinning these effects remains preclinical or derived from early-phase studies, and definitive human data are still awaited
Take 1-3 capsules daily
For example, Wegovy starts at 0.25 mg weekly and increases monthly until reaching the maintenance dose of 2.4 mg weekly
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