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MLN3897 Plus Methotrexate in Patients With Rheumatoid Arthritis: Safety, Efficacy, Pharmacokinetics, and Pharmacodynamics of an Oral CCR1 Antagonist in a Phase IIa, Double-Blind, Placebo-Controlled, Randomized, Proof-of-Concept Study
Other Ingredients: microcrystalline cellulose, acid resistant veggie capsule
Follow-up Repeat broad and inflammation markers after 6-12 weeks if symptoms change or the protocol continues
Where GLP-1 agonists often produce a sensation of fullness and food aversion (sometimes to the point of gastrointestinal discomfort ), amylin-based satiety typically manifests as a more gentle reduction in hunger drive
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