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Supplemental lipoic acid also decreased the serum concentrations of some (IFN-, ICAM-1, TGF-, IL-4), but not all markers (TNF-, IL-6, MMP-9), cytokines and other inflammation (98)
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These findings hint that GLP-1R-based therapeutics may engage epigenetic mechanisms, tentatively explaining their broad efficacy across multiple disorders
It has shown remarkable efficacy in clinical trials for chronic weight management
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