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In addition, the peptide was designed to selectively stimulate GH production in the anterior pituitary without affecting the production of other hormones, such as prolactin and ACTH, which are commonly triggered by other, less selective GHSs [8]

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Summary: GLP-1 hormone is primarily produced by specialised L-cells located in the distal small intestine (ileum) and colon, with the highest concentrations in the ileum and large intestine

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